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Why the viscosity of spicule cream changed? Author: SHINEMIIN Q: How to solve it? A: Do not use the spicule purified by strong alkali and acid Why? Because the hydrochloric acid or NaOH  are used during purification process , due to the porous and hollow structure of spicule, these harmful solvent cannot be completely removed. […]

How do we choose spicule to develop new cosmetic? Author: SHINEMIIN             Sponge spicule(hydrolyzed sponge) are insoluble in any organic solution, and they are hollow and porous, so they can be used as an introduction medium, and a natural raw material for exfoliation and skin rejuvenation.It is no special certificate required, non

How Spicules Improve Skin Author: SHINEMIIN ➤Physical Micro-Stimulation: The core mechanism of action of spicules is that when applied to the skin, the micro-needle structures physically penetrate the stratum corneum and epidermis, creating numerous micro-channels or “micro-damages.”This is similar to micro-needling therapy, but with the difference that it uses biological structures. ➤Inducing a Natural Healing

Journal: J Med Assoc Thai Author: Montree Udompataikul, Montri Wongniraspai, Udomsri Showpittapornchai, Amporn Jariyapongsakul Abstract Objective: To study the effects and safety of Spongilla lacustris (SL) in 3% hydrogen peroxide (H20) on rat skin. Material and method: An experimental study was conducted on 3 groups of Wistar- Furth adult rats. The first group was applied

Journal : Annals of Dermatology, Author: Jeong-min Ha, Cho-ah Lim, Kyuboem Han, Jong-cheon Ha, Hae-eul Lee, YoungLee, Young-joon Seo, Chang-deok Kim, Jeung-hoon Lee.Myung ImPublished date : 2017 Abstract Background: Micro-needle patches have been recently used to increase skin permeability, which improves drug delivery, and for cosmetic purposes. However, these patches may of-ten have limited efficacy

Journal: JKAIS(한국산학기술학회논문지> Author: Seo-Yeon Park. Jae-Nam LeePublished date : 2018 Abstract This study was conducted to investigate the effects of seaweed peeling (SP), glycolic acid peeling (GP) and general scrub (GS), which are widely known as cures for acne in both medicine and esthetics on the keratosis pilaris skin and provide basic data for a

Registration No. : 01663104Registration Date : 2014.02.12Inventor: Villani, MariaNationality : Europe Abstract Therapeutic compositions and methods for using same for treating skin conditions and diseases are disclosed. Treatable skin conditions and diseases include without limitation acne vulgaris, rosacea, seborrheic dermatitis, eczema (atopic dermatitis), psoriasis, photo- aging and actinic keratosisacne vulgaris, psoriasis, photo-aging and eczema. Therapeutic

Journal : Mol Ther Nucleic Acids Author: XueJiao Liang, JiaLiang Zhang, HuiLong Ou, Jun Chen, Samir Mitragotri, Ming Chen Published date : 2020 Abstract We report the topical administration of sponge Haliclona sp. Spicules (SHS) combined with cationic flexible liposomes (CFL) to increase the delivery of small interfering RNA (siRNA) into viable skin cells in

Registration No. : 07604821Registration Date : 2009.10.20Inventor: Maria VillaniNationality : USA Abstract Therapeutic compositions and methods for using same for treating skin conditions and diseases are disclosed. Treatable skin conditions and diseases include, for example, acne vulgaris, rosacea, seborrheic dermatitis, eczema (atopic dermatitis), psoriasis, photo-aging and actinic keratosisacne vulgaris, psoriasis, photo-aging and eczema. Therapeutic compositions

Journal: Asian journal of beauty and cosmetologyAuthor: Lee Chang Ha, Choi Bae SeokPublished date : 2016 Abstract Purpose: Spicule has the ability to peel off the skin’s surface layer and improve acne. Therefore, in this study, we suggest that the microdermabrasion effect of spicule cleanser improves pore keratinization of acne skin and inhibits the proliferation